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Pediatric rhabdomyosarcomas in Tunisia.

Identifieur interne : 000117 ( Main/Exploration ); précédent : 000116; suivant : 000118

Pediatric rhabdomyosarcomas in Tunisia.

Auteurs : Nabiha Missaoui [Tunisie] ; Hanène Landolsi ; Lilia Jaidene ; Affissath Anjorin ; Atef Ben Abdelkader ; Mohamed Tahar Yaacoubi ; Sihem Hmissa

Source :

RBID : pubmed:21198286

Descripteurs français

English descriptors

Abstract

INTRODUCTION

Rhabdomyosarcoma is the most common soft tissue sarcoma in the first two decades of life. Since there is a paucity of reports on the pattern of its occurrence in Tunisia, we here analysed the epidemiological pattern, clinical features, and pathology.

DESIGN

We retrospectively studied 30 consecutive cases of histologically proven rhabdomyosarcoma in children aged 0-15 years extracted from the database of the Cancer Registry of the Center of Tunisia for the period 1993-2007.

RESULTS

Rhabdomyosarcomas represented 53.6% of soft tissue sarcomas and 3.8% of all children cancer cases registered during this period. The male/female ratio was 2.7 with a mean age at diagnosis of 5.9 years. The embryonal subtype was the most frequent (60%) and the two most common sites of disease were the head and neck (50%) and genito-urinary tract(23.3%). Chemotherapy was used in 90% of patients; 43.3% of patients had radical surgery and 26.7% of patients received radiation therapy.

CONCLUSION

The epidemiology, pathology and clinical features of rhabdomyosarcoma in Tunisian children are close to those reported from other countries.


PubMed: 21198286


Affiliations:


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Le document en format XML

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<term>Head and Neck Neoplasms (therapy)</term>
<term>Humans (MeSH)</term>
<term>Infant (MeSH)</term>
<term>Infant, Newborn (MeSH)</term>
<term>Registries (MeSH)</term>
<term>Retrospective Studies (MeSH)</term>
<term>Rhabdomyosarcoma (epidemiology)</term>
<term>Rhabdomyosarcoma (pathology)</term>
<term>Soft Tissue Neoplasms (epidemiology)</term>
<term>Soft Tissue Neoplasms (pathology)</term>
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<term>Enregistrements (MeSH)</term>
<term>Humains (MeSH)</term>
<term>Nourrisson (MeSH)</term>
<term>Nouveau-né (MeSH)</term>
<term>Rhabdomyosarcome (anatomopathologie)</term>
<term>Rhabdomyosarcome (épidémiologie)</term>
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<term>Rhabdomyosarcome</term>
<term>Tumeurs des tissus mous</term>
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<term>Soft Tissue Neoplasms</term>
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<term>Soft Tissue Neoplasms</term>
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<div type="abstract" xml:lang="en">
<p>
<b>INTRODUCTION</b>
</p>
<p>Rhabdomyosarcoma is the most common soft tissue sarcoma in the first two decades of life. Since there is a paucity of reports on the pattern of its occurrence in Tunisia, we here analysed the epidemiological pattern, clinical features, and pathology.</p>
</div>
<div type="abstract" xml:lang="en">
<p>
<b>DESIGN</b>
</p>
<p>We retrospectively studied 30 consecutive cases of histologically proven rhabdomyosarcoma in children aged 0-15 years extracted from the database of the Cancer Registry of the Center of Tunisia for the period 1993-2007.</p>
</div>
<div type="abstract" xml:lang="en">
<p>
<b>RESULTS</b>
</p>
<p>Rhabdomyosarcomas represented 53.6% of soft tissue sarcomas and 3.8% of all children cancer cases registered during this period. The male/female ratio was 2.7 with a mean age at diagnosis of 5.9 years. The embryonal subtype was the most frequent (60%) and the two most common sites of disease were the head and neck (50%) and genito-urinary tract(23.3%). Chemotherapy was used in 90% of patients; 43.3% of patients had radical surgery and 26.7% of patients received radiation therapy.</p>
</div>
<div type="abstract" xml:lang="en">
<p>
<b>CONCLUSION</b>
</p>
<p>The epidemiology, pathology and clinical features of rhabdomyosarcoma in Tunisian children are close to those reported from other countries.</p>
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